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avana skyway yelp Moreover, the math of cost-benefit analy?ses runs aground when it comes to eradication campaigns, because the benefits, in theory, are infinite. That is: No one will ever die from—or spend a dime on vaccinating against—smallpox for the remainder of human history, barring a disaster involving one of the few lingering military stockpiles. According to a 2010 study, polio eradication would generate $40?billion to $50?billion in net benefits by 2035. Looking at a long enough timescale, the eradication of polio could someday be seen as positively cheap.